胡大刚，1986年出生，英国威廉希尔公司教授，博士生导师，“国家优秀青年基金”和“山东省优秀青年基金”获得者，“山东青年创新榜样”，Horticulture Plant Journal、园艺学报和河北农业大学学报编委，Food Quality and Safety青年编委，Frontiers in Plant Science审稿编辑和Agriculture-Basel客座编辑，中国园艺学会理事。2019年4月至2020年9月在美国康奈尔大学从事博士后研究；现被聘为“山东省现代设施果树技术创新中心外聘专家” 、“重庆市三江人才”和“泰安市科普志愿者专家”；“全国大学生创新创业大赛”和“山东省研究生优秀成果奖”优秀指导教师；在国际及国内重要学术会议上作学术报告10余次；目前承担本科生和研究生《园艺学科前沿专题讲座》和《园艺植物生物技术》等课程的教学工作；主持国家自然基金面上项目等国家及省部级课题8余项；以第一完成人获齐鲁农业科技奖二等奖1项；近5年发表学术论著50余篇，发表期刊包括SCI和国内核心期刊，累积影响因子超过300。其中第一作者论文10篇，主要发表在New Phytologist、PLOS Genetics、Plant Physiology和Plant Journal等国外著名植物学期刊上；通讯作者论文40余篇，主要发表在Plant Physiology、Plant Biotechnology Journal、Horticulture Research和Plant Cell and Physiology等国外著名植物学期刊上；两篇论文被Web of Science定义为前1%高被引论文。参编教材5部，申请或授权发明专利6项；曾应邀为New Phytologist, Plant Biotechnology Jounal, Journal of Agricultural and Food Chemistry及 Horticulture Research等国际著名期刊审稿50余篇。
研究方向简介：
1、苹果果实品质的形成与调控。从苹果果实的糖酸代谢和运输入手，研究了它们的合成、运输和液泡贮存；然后，从糖酸积累相关基因的环境和内部信号响应切入，揭示了适度胁迫等促进糖酸积累、改善果实品质的机理。
2、苹果果实品质保持的机理与调控。研究采后苹果果实失水、果肉软化和风味保持的调控机理，并研发配套的苹果果实保鲜新技术；同时揭示采后苹果果实病害发生的分子机理，寻求降低采后果实病害的调控措施，最终减少采后苹果果实的腐烂率。
代表性研究论文：
●Yu, J. Q., Gu, K. D., Zhang, L. L., Sun, C. H., Zhang, Q. Y., Wang, J. H., Wang C. K., Wang, W. Y., Du, M. C., Hu, D. G.* (2022). MdbHLH3 modulates apple soluble sugar content by activating phosphofructokinase gene expression. Journal of Integrative Plant Biology, https://doi.org/10.1111/jipb.13236.
●Yu, J. Q., Gu, K. D., Sun, C. H., Zhang, Q. Y., Wang, J. H., Ma, F. F., You C. X., Hu D. G.*, Hao, Y. J.* (2021). The apple bHLH transcription factor MdbHLH3 functions in determining the fruit carbohydrates and malate. Plant Biotechnology Journal, 19(2), 285-299.
●Gu, K. D., Zhang, Q. Y., Yu, J. Q., Wang, J. H., Zhang, F. J., Wang, C. K., Zhao Y. W., Sun C. H., You C. X., Hu D. G.*, Hao, Y. J.* (2021). R2R3-MYB transcription factor MdMYB73 confers increased resistance to the fungal pathogen Botryosphaeria dothidea in apples via the salicylic acid pathway. Journal of Agricultural and Food Chemistry, 69(1), 447-458.
● Hu D.G.#, Wang N.#, Wang D.H.#, Cheng L., Wang Y.X., Zhao Y.W.., Ding J.Y., Gu K.D., Xiao X., Hao Y.J.* (2020) A basic/helix-loop-helix transcription factor controls leaf shape by regulating auxin signaling in apple. New Phytologist,228(6), 1897-1913.
●Zhang, Q.Y., Gu, K.D., Cheng, L., Wang, J.H., Yu, J.Q., Wang, X.F., You, C.X., Hu D.G.*, Hao, Y.J.* (2020) BTB-TAZ domain protein MdBT2 modulates malate accumulation and vacuolar acidification in response to nitrate. Plant Physiology, DOI:10.1104/pp.20.00208.
●Yu, J.Q., Gu, K.D., Sun, C.H., Zhang, Q.Y., Wang, J.H., Ma, F.F., You C.X., Hu D.G.*, Hao, Y.J.* (2020). The apple bHLH transcription factor MdbHLH3 functions in determining the fruit carbohydrates and malate. Plant Biotechnology Journal, doi.org/10.1111/pbi.13461.
● Hu D.G., Sun C.H., Zhang Q.Y., Gu K.D., Hao Y.J.* (2020) The basic helix-loop-helix transcription factor MdbHLH3 modulates leaf senescence in apple via the regulation of dehydratase-enolase-phosphatase complex 1. Horticulture Research, 7, 50.
● Hu D.G., Yu J.Q., Han P.L., Xie X.B., Sun C.H., Zhang Q.Y., Wang J.H., Hao Y.J.* (2019) The regulatory module MdPUB29-MdbHLH3 connects ethylene biosynthesis with fruit quality in apple. New Phytologist, 221, 1966-1982.
●Sun M.H.#, Ma Q.J.#, Hu D.G.#, Zhu X.P., You C.X., Shu H.R., Hao Y.J.* (2018) The glucose sensor MdHXK1 phosphorylates a tonoplast Na+/H+ exchanger to improve salt tolerance. Plant Physiology, 176(4), 2977-2990.
● Hu D.G., Li Y.Y., Zhang Q.Y., Li M., Sun C.H., Yu J.Q., Hao Y.J.* (2017) R2R3-MYB transcription factor MdMYB73 is involved in malate accumulation and vacuolar acidification in apple. The Plant Journal, 91, 443-454.
● Hu D.G., Sun C.H., Ma Q.J., You C.X., Cheng L., Hao Y.J.* (2016) MdMYB1 regulates anthocyanin and malate accumulation by directly facilitating their transport into vacuoles in apples. Plant Physiology, 170(3), 1315-1330.
● Hu D.G., Sun C.H., Zhang Q.Y., An J.P., You C.X., Hao Y.J.* (2016) Glucose sensor MdHXK1 phosphorylates and stabilizes MdbHLH3 to promote anthocyanin biosynthesis in apple. PLOS Genetics, 12(8), e1006273.
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